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Cornea Department

Overview

The cornea is front transparent window of the eye through which light enters the eye. 

Diseases affecting the cornea are a major cause of blindness all over the world, second only to cataract in overall importance. A range of infectious and inflammatory eye conditions affect the transparency of the cornea and cause corneal blindness. They add a substantial burden to the community in general and healthcare resources in particular all over the world. Further, individuals with corneal blindness are usually of a younger age group compared with those suffering from cataract. Hence, in terms of total blind years, the impact of corneal blindness is greater.

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Who We Are

The Department of Cornea, Refractive and Anterior Segment at Dr. Shroff’s Charity Eye Hospital was set up in the year 1998 and has grown exponentially since then.

The department provides a myriad of services including medical and surgical treatment of corneal infections, corneal opacities, ectasia, trauma and chemical injury, ocular surface diseases and refractive surgery. We routinely perform complicated and uncomplicated cataract surgeries, have a dedicated microbiology and histopathology laboratory for eye diseases, a contact lens service that provides customized lenses, and a state of the art research facility with current area of interest in stem cells. Our eye bank is the biggest in north India and provides tissues to our own HOTA certified secondary centres set up across North India and to other corneal facilities as well.

In addition to our clinical and research facilities, we also train short-term and long-term fellows in various anterior segment and corneal procedures.

Key Facts & Figures for year 2023 - 24

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Patients Seen
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Surgeries
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Refractive Surgeries
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Keratoplasties*

* A total of 738 keratoplasties were done, of which 25 % were performed at our HOTA certified secondary centres

Our Experts

manisha
Dr. Manisha Acharya
Director - Cornea Services (SCEH Network) & Director - SCEH Eye Bank
nikita
Dr. Nidhi Gupta
Consultant – Cornea, Anterior Segment & Refractive Services
nupur
Dr. Nupur Gupta
Consultant - Cornea, Anterior Segment & Refractive Services
nikunj
Dr. Nikunj V. Patel
Consultant - Cornea, Anterior Segment & Refractive Services
isha
Dr. Isha Chaudhari
Consultant, Anterior Segment, Cornea and Refractive services
Dr. Natasha Kaul (2)
Dr. Natasha Koul
Consultant, Anterior Segment and Corneal services

Diagnosis & Treatment

The clinic evaluates and treats patients with cornea and external eye diseases. State-of-the-art diagnostic facilities include corneal topography (Orbscan IIz & Pentacam), meibomography, AS-OCT, specular microscopy, ultrasonic pachymetry, and Cmicroscopy. Refractive surgery performed in the department includes Femto assisted LASIK, Microkeratome based LASIK and Photorefractive Keratectomy.

Conditions We Treat

We treat a wide variety of corneal infections due to microbes like bacteria, virus, and fungus. A corneal infection can cause a perforation in the cornea if left unchecked, or can lead to a corneal opacity. We have the whole armamentarium of medical and surgical treatments available to cure them and rehabilitate in case an opacity develops.

A corneal opacity is the whiteness on the transparent cornea that decreases vision when present in the center and is cosmetically unsightly. We perform corneal transplant surgery to improve vision in case of central corneal opacities and perform colouring of the opacity called tattooing when the indication is cosmesis.

Corneal ectasias is where the shape of the cornea changes due to progressive thinning. We provide treatment for halting the progression as well as correcting the vision.

From a farmer who suffered an injury while working in the field, to an acid victim, to children with thermal burns, we see such stories everyday in our clinics. We are equipped with manpower and willpower to bring them back to normal life and help them see better with their eyes.

We have specialists to deal with uneven unsightly corneas affected from diseases like Steven Johnson Syndrome, Ocular Cicatricial Pemphigoid, chemical burns and offer the latest stem cell based therapies and eyelid skin grafting procedures to such patients.

Our eye surgeons have become among the most trusted experts in refractive surgeries, having performed countless successful procedures over the course of their careers—and helping patients get an improved “outlook on life”.

Routinely performed procedures

  • Corneal Transplantation
  • Penetrating Keratoplasty (Optical / Therapeutic / Tectonic / Cosmetic)
  • Lameller Keratoplasty (DSAEK / DSEK / DMEK / DALK)
  • Amniotic Membrane Transplantation
  • Pterygium Surgery with Fibrin Glue
  • Ocular Trauma Management
  • Refractive Laser Surgery (LASIK) and Wave Front Guided Customized LASIK / PRK and FEMTO LASIK Surgery
  • Limbal Stem Cell Transplantation
  • Management of Conjunctival Tumours
  • Keratoprosthesis
  • Ocular Surface Reconstructive Surgeries
  • Rose K Contact Lenses and Collagen Cross Linking with Riboflavin (C3R) for Keratoconus Patients
  • Corneal Tattooing
Routinely Performed Procedures

Other Facilities

Eye banking services

Contact Lens Centre

Patient Stories

Prescribing Hope

A 32 years old woman, residing in Sambal district, Uttar Pradesh, first came to us nine years back, in 2014,...

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Thinking out of the box.

“A good teacher can inspire hope, ignite the imagination, and instill a love of learning” – Brad Henry This is...

Read More...

OUR EDUCATION, PUBLICATIONS & RESEARCH FIGURES (2022)​

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Short-term Fellows
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Long-term Fellows
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Publications
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Research Grants

Education

Long Term Ophthalmology Fellowship

Fellowship in Cornea & Anterior Segment

Short term Ophthalmology fellowship

Cornea & Anterior Segment

Following Training Courses In Recent Past

ILEAP 2022* | DSAEK | MMG | SLET | LASIK

* Training on Minor OT procedures, both didactic and hands-on

RESEARCH

MAJOR PUBLICATIONS

  • Three Consecutive Cases of Ocular Polyhexamethylene Biguanide (PHMB) Toxicity Due to Compounding Error.

    Patel, N.V., Mathur, U., Sawant, S., Acharya, M., Gandhi, A. and Sawant Sr, S., 2023. Three Consecutive Cases of Ocular Polyhexamethylene Biguanide (PHMB) Toxicity Due to Compounding Error. Cureus, 15(5).
  • Single-Staged Surgical Correction of Eyelid Sequelae Along With Lid Margin Mucous Membrane Grafting in Stevens-Johnson Syndrome and Other Cicatricial Ocular Surface Diseases.

    Shree, N., Das, S., Arya, D., Srivastava, A., Singh, A. and Sangwan, V., 2023. Single-staged surgical correction of eyelid sequelae along with lid margin mucous membrane grafting in Stevens–Johnson syndrome and other cicatricial ocular surface diseases. Cornea, 42(4), pp.404-411.
  • Management of cataract in dry eye disease: Preferred practice pattern guidelines.

    Donthineni, P.R., Deshmukh, R., Ramamurthy, C., Sangwan, V.S., Mehta, J.S. and Basu, S., 2023. Management of cataract in dry eye disease: Preferred practice pattern guidelines. Indian Journal of Ophthalmology, 71(4), pp.1364-1372.
  • Leveraging neural crest pluripotency to extend retinal and craniofacial niches for building neurovascular organoids—a theranostic and drug development perspective.

    Sharma, M., Jangra, S., Dhiman, S., Yangzes, S., Tiwari, A., Patro, S.K., Sharma, K., Rathore, S., Ramavat, A.S., Chhabra, S. Sangwan VS, and Panigrahi, I., 2023. Leveraging neural crest pluripotency to extend retinal and craniofacial niches for building neurovascular organoids—a theranostic and drug development perspective. In The Eye (pp. 55-118). Academic Press.
  • A rare case of Urrets-Zavalia syndrome following trabeculectomy in a pediatric patient. Indian Journal of Ophthalmology.

    Johri, T. and Dubey, S., 2023. A rare case of Urrets-Zavalia syndrome following trabeculectomy in a pediatric patient. Indian Journal of Ophthalmology-Case Reports, 3(2), pp.364-367.
  • Role of Binocular Vision Therapy for Spasm of Near Reflex (SNR): A Case Report

    Sharma, P., Singh, P.K. and Ganesh, S., 2023. Role of Binocular Vision Therapy for Spasm of Near Reflex (SNR): A Case Report. J Ophthal Ocu Therap. (JOOT)
  • Bilateral Apogeotropic Lateral Canal BPPV: Role of Secondary Signs of Lateralization in Diagnosis

    Kumar, S., Gupta, N., Dorasala, S. et al I Indian Journal of Otolaryngology and Head & Neck Surgery
  • The impact of oral and systemic medications on the eye.

    Sabherwal, S. and Mohamed-Ahmed, A.H., 2023. The impact of oral and systemic medications on the eye. Community eye health, 36(118), p.14.
  • A goat eye, wet lab model for training in Descemet membrane endothelial keratoplasty.

    Gupta, N., Bhogal, M., Vaddavalli, P.K., Boldini, A., Semeraro, F., Varshney, A. and Romano, V., 2023. A goat eye, wet lab model for training in Descemet membrane endothelial keratoplasty. Indian Journal of Ophthalmology, 71(5), pp.2230-2233.
  • Giant facial congenital melanocytic nevus associated with conjunctival melanoma.

    Shree, N., Gandhi, A. and Das, S., 2023. Giant facial congenital melanocytic nevus associated with conjunctival melanoma. Orbit, pp.1-4.
  • Evaluation of dry eyes in children with vernal kerato-conjunctivitis using clinical tests and ocular surface analysis.

    Gupta, S., Rahman, M., Tibrewal, S., Gaur, A., Ganesh, S. and Sangwan, V.S., 2023. Evaluation of dry eyes in children with vernal kerato-conjunctivitis using clinical tests and ocular surface analysis. Indian Journal of Ophthalmology, 71(4), pp.1488-1494.
  • An unusual complication after cataract surgery may suggest the possibility of underlying rhino-orbital mucormycosis

    Gupta N. | Indian J Ophthalmol. 2023 Jan;71(1):310-311. doi: 10.4103/ijo.IJO_1506_22. PMID: 36588264
  • Efficacy and safety of 0.05% micellar nano-particulate (MNP) cyclosporine ophthalmic emulsion in the treatment of moderate-to-severe keratoconjunctivitis sicca: a 12-week, multicenter, randomized, active-controlled trial

    Rao AT, Gupta A, Chauhan T, Basu S, Batra N, Sharma N, Sangwan VS, Gupta V,Mukherjee S I BMC Ophthalmol. 2023 Mar 27;23(1):121. doi:10.1186/s12886-023-02838-z.
  • Managing chronic inflammation in ocular sequelae of Stevens Johnson Syndrome to restore vision

    Gupta N, Singh G, Bashir H, Sangwan V, Mathur U I Ocul Surf. 2023 Jan 27:S1542-0124(23)00014-9. doi: 10.1016/j.jtos.2023.01.008. Epub ahead of print. PMID: 36717075
  • Endoscopic Management of Severe Ocular Symptoms Secondary to the Missed Paranasal Sinus Mucoceles.Springer Nature Chapter in Video Atlas

    Gupta, N I doi.org/10.1007/978-981-19-9712-9
  • Corneal stem cells niche and homeostasis impacts in regenerative medicine; concise review

    Tavakkoli F, Eleiwa TK, Elhusseiny AM, Damala M, Rai AK, Cheraqpour K, Ansari MH, Doroudian M, H Keshel S, Soleimani M, Djalilian AR, Sangwan VS, Singh V I Eur J Ophthalmol. 2023 Jan 5:11206721221150065. doi: 10.1177/11206721221150065. Epub ahead of print. PMID: 36604831
  • Herpes simplex viral keratitis - A mixed bag of challenging case scenarios

    Singh A, Acharya M I Indian J Ophthalmol Case Rep 2023;3:58-60.
  • Endoscopic Management of Severe Ocular Symptoms Secondary to the Missed Paranasal Sinus Mucoceles.Springer Nature Chapter in Video Atlas.2023 Jan

    Gupta, N I doi.org/10.1007/978-981-19-9712-9
  • Corneal stem cells niche and homeostasis impacts in regenerative medicine; concise review

    Tavakkoli F, Eleiwa TK, Elhusseiny AM, Damala M, Rai AK, Cheraqpour K, Ansari MH, Doroudian M, H Keshel S, Soleimani M, Djalilian AR, Sangwan VS, Singh V I Eur J Ophthalmol. 2023 Jan 5:11206721221150065. doi: 10.1177/11206721221150065. Epub ahead of print. PMID: 36604831
  • Commentary: Precision - The hallmark of refractive surgery

    Singh A, Acharya M | Indian J Ophthalmol. 2023 Jan;71(1):69. doi: 10.4103 | ijo.IJO_2256_22. PMID: 36588210
  • Herpes simplex viral keratitis - A mixed bag of challenging case scenarios

    Singh A, Acharya M I Indian J Ophthalmol Case Rep 2023;3:58-60

Projects

LiQd Cornea- Supported by Pandorum

The aim of the project is to design a bio-engineered bio-material which can be used as a liquid drop instead of a conventional corneal transplant: the immediate indication for liquid cornea is neurotrophic keratitis, macular to leucomatous corneal scars, keratoconus, corneal perforations, persistent epithelial defects etc.

PED study project - Funded by DST grant

The main objective of the project is to test the expression of KLF4 in persistent corneal epithelial defects (PCED) and correlating with the disease severity and KLF4 knockdown in corneal epithelial cells recapitulate PCED pathology and can be rescued by overexpressing KLF4                                                                                       

Why SCEH

At Dr. Shroff’s Charity Eye Hospital, we offer the best cornea treatment in Delhi and north India. We rank among the top ten hospitals for cornea transplant surgery in India. During the corneal transplant surgery, the patient is given anesthesia depending on the age, medical history, and eye problem. We pride ourselves in offering the best cornea treatment as we have some of the finest cornea specialist doctors. Also, corneal transplant cost in India is economical and cost-effective than other countries.

Dr. Shroff’s Charity Eye Hospital is ranked among first-in-class for its clinical excellence, the enduring legacy of our founder, Dr. S. P. Shroff. We have state-of-the-art clinical care providing best eye care and treatment to our patients.

Our team comprises of eminent doctors from the world, most of whom are pioneers in their respective fields. Additionally, they are renowned for developing innovative and revolutionary clinical procedures.

For more queries on cornea eye treatment or corneal transplant surgery in Delhi and north India, contact us at +91-11- 4352 4444 email: sceh@sceh.net